The Odyssey Flu Trial

  • Status: Open to Recruitment 
  • Population: Adult 
  • Disease group: Flu 
  • Funder: Moderna  
  • Sponsor: Moderna 
  • Principal Investigator: Prof. Paul Heath 

Study Aims  

Bird flu and pig flu are examples of diseases caused by global influenza that, in rare cases, can change and infect humans.1 Preparing for potential new outbreaks by researching investigational vaccines could possibly limit global illnesses, hospitalisations and death. 

The Odyssey Trial will assess the safety and immune responses to several investigational vaccines aimed at preventing global influenza outbreaks. Joining this clinical trial will not only help advance research of investigational mRNA flu vaccines but may also help investigational vaccine development for other infectious diseases.  

What does participating in this study involve? 

Your participation in the Odyssey Trial should last about 7 months. 

  • You will have a total of 7 scheduled clinic visits and 4 scheduled phone calls to check in about any side effects
  • You will be given 1 injection in the upper arm during your first clinic visit (Day 1), and 1 injection in the upper arm during your third clinic visit (about Day 22)
  • You will have blood taken during some clinic visits
  • You must enter whether you experience any flu symptoms and/or side effects into a symptom reporting electronic diary (eDiary) every day for 7 days after receiving each injection
  • Enrolling in this clinical trial is completely your choice. You may stop participating in the clinical trial at any time, and you do not have to give a reason for doing so
  • Compensation for your trial-related time may be provided

If you would like to hear more about this trial, please visit the study website:

To learn more, please look at the Participant Information Sheet